2-Trifluoromethyl-6-chloro-5-pyridineboric acid

2-Trifluoromethyl-6-chloro-5-pyridineboric acid - Names and Identifiers

Name	2-Trifluoromethyl-6-chloro-5-pyridineboric acid
Synonyms	2-TRIFLUOROMETHYL-6-CHLORO-5-PYRIDINEBORIC ACID 6-Chloro-2-trifluoromethyl-5-pyridineboric acid 2-Chloro-6-trifluoromethylpyridin-3-bronic aicd 2-Trifluoromethyl-6-chloro-5-pyridineboric acid 2-(TRIFLUOROMETHYL)-6-CHLORO-5-PYRIDINEBORONIC ACID 2-Chloro-6-(trifluoromethyl)pyridine-3-boronic Acid [2-chloro-6-(trifluoromethyl)-3-pyridinyl]boronic acid [2-Chloro-6-(trifluoromethyl)-3-pyridinyl]boronic acid [2-Chloro-6-(trifluoromethyl)pyridin-3-yl]boronic acid (2-Chloro-6-(trifluoroMethyl)pyridin-3-yl)boronic acid 2-chloro-6-(trifluoroMethyl)pyridin-3-yl-3-boronic acid Boronic acid, B-[2-chloro-6-(trifluoromethyl)-3-pyridinyl]-
CAS	205240-63-7
InChI	InChI=1/C6H4BClF3NO2/c8-5-3(7(13)14)1-2-4(12-5)6(9,10)11/h1-2,13-14H

2-Trifluoromethyl-6-chloro-5-pyridineboric acid - Physico-chemical Properties

Molecular Formula	C6H4BClF3NO2
Molar Mass	225.36
Density	1.57±0.1 g/cm3(Predicted)
Boling Point	298.9±50.0 °C(Predicted)
Flash Point	134.54°C
Vapor Presure	0.001mmHg at 25°C
pKa	5.83±0.58(Predicted)
Storage Condition	Inert atmosphere,Store in freezer, under -20°C
Refractive Index	1.483

2-Trifluoromethyl-6-chloro-5-pyridineboric acid - Introduction

acid is an organic compound with the formula C6H3BClF3NO2. The following is a description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Colorless crystals or white solids.
-Solubility: Soluble in organic solvents such as ethanol and dimethylformamide, insoluble in water.
-Melting point: About 120-122 ° C.
-Stability: Stable at room temperature, but avoid contact with strong oxidants and reducing agents.

Use:
-acid is often used as an important reagent in organic synthesis, especially in metal organic chemistry and transition metal catalytic reactions.
-It can be used as an acidic catalyst in organic synthesis, a transition metal ligand and a catalyst for cross-coupling reactions.

Method:
The preparation of acid can use a variety of methods, one of the common methods is to obtain the product by the reaction of pyridine and tetraethyl trifluoromethylborate in the presence of aluminum chloride.

Safety Information:
-the acid is generally safe under normal conditions of use.
-However, it is still necessary to take appropriate chemical laboratory operations and protective measures, such as wearing protective glasses and gloves, and ensure that the operation is carried out in a well-ventilated area.
-Avoid contact with oxidizing agents, reducing agents and strong acids during storage and handling to avoid dangerous reactions.
-In case of accidental inhalation or contact with skin and eyes, rinse immediately with plenty of water and seek medical help.

Last Update：2024-04-10 22:29:15